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Article

Adult classical glioblastoma with a BRAF V600E mutation.

World journal of surgical oncology - 11 Mar 2015

Takahashi Yoshinobu, Akahane Toshiaki, Sawada Takahiro, Ikeda Hidetoshi, Tempaku Akira, Yamauchi Shigeru, Nishihara Hiroshi, Tanaka Shinya, Nitta Kazumi, Ide Wataru, Hashimoto Ikuo, Kamada Hajime

Abstract excerpt

The B-Raf proto-oncogene serine/threonine kinase (B-Raf) is a member of the Raf kinase family. The BRAF V600E mutation occurs frequently in certain brain tumors such as pleomorphic xanthoastrocytoma, ganglioglioma, and pilocytic astrocytoma, and less frequently in epithelioid and giant cell glioblastoma. BRAF V600E mutation in these cases has been canonically detected using Sanger sequencing or...

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Identifiers

PMID: 25885250
DOI: 10.1186/s12957-015-0521-x
PMCID: PMC4358908

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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