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Integrated molecular and clinical analysis of BRAF-mutant glioma in adults

28 Feb 2023

Abstract excerpt

Abstract BRAF mutations are a significant driver of disease in pediatric low-grade glioma, but the implications of BRAF alterations on the clinical course and treatment response in adult glioma remain unclear. Here, we characterize a multi-institutional cohort of more than 300 patients (>200 adults) with BRAF-mutated glioma using clinical, pathological/molecular, and outcome data. We observed that adult and...

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PMID: 36854806
DOI: 10.1038/s41698-023-00359-y

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