Article
Comparative survival analysis of 12 histidine kinase mutants of Deinococcus radiodurans after exposure to DNA-damaging agents.
Bioprocess and biosystems engineering - 1 Jun 2013
Im Seonghun, Song Dusup, Joe Minho, Kim Dongho, Park Don-Hee, Lim Sangyong
Abstract excerpt
Bacteria are able to adapt to changes in the environment using two-component signal transduction systems (TCSs) composed of a histidine kinase (HK) and a response regulator (RR). Deinococcus radiodurans, one of the most resistant organisms to ionizing radiation, has 20 putative HKs and 25 putative RRs. In this study, we constructed 12 D. radiodurans mutant strains lacking a gene encoding a HK and surveyed their...
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