Article
Association of Dectin-1 and DC-SIGN gene single nucleotide polymorphisms with fungal keratitis in the northern Han Chinese population.
Molecular vision - 1 Jan 2015
Qu Xiaoli, Che Chengye, Gao Ang, Lin Jing, Wang Nan, Du Xing, Liu Ying, Guo Yanli, Chen Wenjun, Zhao Guiqiu
Abstract excerpt
PURPOSE: Dendritic cell-associated C-type lectin-1 (Dectin-1) and dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) play a crucial role in the early procedure of fungal pathogen defenses. The present study evaluated the associations between Dectin-1 and DC-SIGN gene single nucleotide polymorphisms (SNPs) and susceptibility to fungal keratitis (FK) in the northern Han...
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