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Article

Innate and Adaptive Gene Single Nucleotide Polymorphisms Associated With Susceptibility of Severe Inflammatory Complications in Acanthamoeba Keratitis.

Investigative ophthalmology & visual science - 1 Mar 2021

Carnt Nicole A, Pang Ignatius, Burdon Kathryn P, Calder Virginia, Dart John K, Subedi Dinesh, Hardcastle Alison J

Abstract excerpt

Purpose: Over a third of patients with Acanthamoeba keratitis (AK) experience severe inflammatory complications (SICs). This study aimed to determine if some contact lens (CL) wearers with AK were predisposed to SICs due to variations in key immune genes. Methods: CL wearers with AK who attended Moorfields Eye Hospital were recruited prospectively between April 2013 and October 2014. SICs were defined as...

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Identifiers

PMID: 33755043
DOI: 10.1167/iovs.62.3.33
PMCID: PMC7991962

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