Article
Association of TLR2 and TLR4 gene single nucleotide polymorphisms with Fungal Keratitis in Chinese Han population.
Current eye research - 1 Jan 2014
Wang N, Zhao G Q, Gao A, Che C Y, Qu X L, Liu Y, Guo Y L
Abstract excerpt
PURPOSE: Toll-like receptor 2 (TLR2) and Toll-like receptor 4 (TLR4) play a crucial role in the primary defense against fungal pathogens, and since genetic variation in genes may regulate the response. This study aimed to test whether variants in the TLR4 gene are associated with fungal keratitis (FK) of Chinese Han population. MATERIALS AND METHODS: Two-hundred sixty-nine subjects (109 cases and 160 matched...
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