Article
Construction of a virtual Mycobacterium tuberculosis consensus genome and its application to data from a next generation sequencer.
BMC genomics - 20 Mar 2015
Okumura Kayo, Kato Masako, Kirikae Teruo, Kayano Mitsunori, Miyoshi-Akiyama Tohru
Abstract excerpt
BACKGROUND: Although Mycobacterium tuberculosis isolates are consisted of several different lineages and the epidemiology analyses are usually assessed relative to a particular reference genome, M. tuberculosis H37Rv, which might introduce some biased results. Those analyses are essentially based genome sequence information of M. tuberculosis and could be performed in sillico in theory, with whole genome sequence...
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