Article
TGS-TB: Total Genotyping Solution for Mycobacterium tuberculosis Using Short-Read Whole-Genome Sequencing.
PloS one - 1 Jan 2015
Sekizuka Tsuyoshi, Yamashita Akifumi, Murase Yoshiro, Iwamoto Tomotada, Mitarai Satoshi, Kato Seiya, Kuroda Makoto
Abstract excerpt
Whole-genome sequencing (WGS) with next-generation DNA sequencing (NGS) is an increasingly accessible and affordable method for genotyping hundreds of Mycobacterium tuberculosis (Mtb) isolates, leading to more effective epidemiological studies involving single nucleotide variations (SNVs) in core genomic sequences based on molecular evolution. We developed an all-in-one web-based tool for genotyping Mtb, referred...
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