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Article

Clonality and micro-diversity of a nationwide spreading genotype of Mycobacterium tuberculosis in Japan.

PloS one - 1 Jan 2015

Wada Takayuki, Iwamoto Tomotada, Tamaru Aki, Seto Junji, Ahiko Tadayuki, Yamamoto Kaori, Hase Atushi, Maeda Shinji, Yamamoto Taro

Abstract excerpt

Mycobacterium tuberculosis transmission routes can be estimated from genotypic analysis of clinical isolates from patients. In Japan, still a middle-incidence country of TB, a unique genotype strain designated as 'M-strain' has been isolated nationwide recently. To ascertain the history of the wide spread of the strain, 10 clinical isolates from different areas were subjected to genome-wide analysis based on deep...

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Identifiers

PMID: 25734518
DOI: 10.1371/journal.pone.0118495
PMCID: PMC4348518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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