Article
Genomics and Machine Learning for Taxonomy Consensus: The Mycobacterium tuberculosis Complex Paradigm.
PloS one - 1 Jan 2015
Azé Jérôme, Sola Christophe, Zhang Jian, Lafosse-Marin Florian, Yasmin Memona, Siddiqui Rubina, Kremer Kristin, van Soolingen Dick, Refrégier Guislaine
Abstract excerpt
Infra-species taxonomy is a prerequisite to compare features such as virulence in different pathogen lineages. Mycobacterium tuberculosis complex taxonomy has rapidly evolved in the last 20 years through intensive clinical isolation, advances in sequencing and in the description of fast-evolving loci (CRISPR and MIRU-VNTR). On-line tools to describe new isolates have been set up based on known diversity either on...
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