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Article

Hepatitis C Virus: Viral Quasispecies and Genotypes.

International journal of molecular sciences - 22 Dec 2017

Tsukiyama-Kohara Kyoko, Kohara Michinori

Abstract excerpt

Hepatitis C virus (HCV) mainly replicates in the cytoplasm, where it easily establishes persistent infection, resulting in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Due to its high rate of mutation, HCV forms viral quasispecies, categorized based on the highly variable regions in the envelope protein and nonstructural 5A protein. HCV possesses seven major genotypes, among which genotype 1...

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Identifiers

PMID: 29271914
DOI: 10.3390/ijms19010023
PMCID: PMC5795974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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