Article
The Ubp15 deubiquitinase promotes timely entry into S phase in Saccharomyces cerevisiae.
Molecular biology of the cell - 15 Jun 2015
Ostapenko Denis, Burton Janet L, Solomon Mark J
Abstract excerpt
The anaphase-promoting complex in partnership with its activator, Cdh1, is an E3 ubiquitin ligase responsible for targeting cell cycle proteins during G1 phase. In the budding yeast Saccharomyces cerevisiae, Cdh1 associates with the deubiquitinating enzyme Ubp15, but the significance of this interaction is unclear. To better understand the physiological role(s) of Ubp15, we examined cell cycle phenotypes of cells...
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