Article
Temporal requirement for SMN in motoneuron development.
Human molecular genetics - 1 Jul 2013
Hao Le T, Duy Phan Q, Jontes James D, Wolman Marc, Granato Michael, Beattie Christine E
Abstract excerpt
Proper function of the motor unit is dependent upon the correct development of dendrites and axons. The infant/childhood onset motoneuron disease spinal muscular atrophy (SMA), caused by low levels of the survival motor neuron (SMN) protein, is characterized by muscle denervation and paralysis. A...
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