Article
Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling.
Science (New York, N.Y.) - 11 Apr 2008
Gallarda Benjamin W, Bonanomi Dario, Müller Daniel, Brown Arthur, Alaynick William A, Andrews Shane E, Lemke Greg, Pfaff Samuel L, Marquardt Till
Abstract excerpt
Execution of motor behaviors relies on circuitries effectively integrating immediate sensory feedback to efferent pathways controlling muscle activity. It remains unclear how, during neuromuscular circuit assembly, sensory and motor projections become incorporated into tightly coordinated, yet functionally separate pathways. We report that, within axial nerves, establishment of discrete afferent and efferent...
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