Article
Comparison of custom capture for targeted next-generation DNA sequencing.
The Journal of molecular diagnostics : JMD - 1 Jan 2015
Samorodnitsky Eric, Datta Jharna, Jewell Benjamin M, Hagopian Raffi, Miya Jharna, Wing Michele R, Damodaran Senthilkumar, Lippus Juliana M, Reeser Julie W, Bhatt Darshna, Timmers Cynthia D, Roychowdhury Sameek
Abstract excerpt
Targeted, capture-based DNA sequencing is a cost-effective method to focus sequencing on a coding region or other customized region of the genome. There are multiple targeted sequencing methods available, but none has been systematically investigated and compared. We evaluated four commercially available custom-targeted DNA technologies for next-generation sequencing with respect to on-target sequencing,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.