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Article

Macrophage Polarization during Murine Lyme Borreliosis

13 Apr 2015

Abstract excerpt

Infection of C3H mice with Borrelia burgdorferi, the causative agent of Lyme disease, reliably produces an infectious arthritis and carditis that peak around 3 weeks postinfection and then spontaneously resolve. Macrophage polarization has been suggested to drive inflammation, the clearance of bacteria, and tissue repair and resolution in a variety of infectious disease models. During Lyme disease it is clear...

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PMID: 25870230
DOI: 10.1128/iai.00369-15

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