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Advanced Age Impairs Macrophage Polarization

16 Dec 2011

Abstract excerpt

Aging affects many aspects of the cellular function of macrophages. Macrophages play a critical role in innate immunity, acting as sentinels to fight pathogens, promoting wound healing, and orchestrating the development of the specific acquired immune response. However, little is known about how age influences the ability of macrophage to change phenotypes in response to environmental factors. This study examined...

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PMID: 22175541
DOI: 10.1089/jir.2011.0058

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