Article

Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

2021-03-02

Abstract excerpt

<title>Abstract</title> <underline>Background:</underline> Macrophages play prominent roles in bacteria recognition and clearance, including <italic>Borrelia burgdorferi</italic> (<italic>Bb</italic>), the Lyme disease spirochete. To elucidate mechanisms by which MyD88/TLR signaling enhances clearance of <italic>Bb </italic>by macrophages, we studied wildtype (WT) and MyD88-/- <italic>Bb</italic>-st...

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Literature Corpus work: 57cc31ab-7e5a-549c-9ce6-892a2c414f28
DOI: 10.21203/rs.3.rs-279261/v1

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