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Macrophage mediated recognition and clearance of <i>Borrelia burgdorferi</i> nelicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

2019-03-30

Abstract excerpt

Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi (Bb). It is believed that the robust inflammatory response induced by the host’s innate immune system is responsible for the clinical manifestations associated with Bb infection. The macrophage plays a central role in the immune response to many bacterial infections and is thought to play a central role in activation of the innate...

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Literature Corpus work
d452a684-ba67-5d7d-b742-af15623174b1
DOI
10.1101/593566
Open publication

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