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Article

<i>Coxiella burnetii</i>, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages

18 Mar 2008

Abstract excerpt

Coxiella burnetii is an obligate intracellular bacterium, responsible for Q fever, which survives in macrophages by interfering with their microbicidal competence. As functional polarization of macrophages is critical for their microbicidal activity, we studied the activation program of monocyte-derived macrophages (MDM) stimulated with C. burnetii. This program was markedly distinct from that induced by...

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PMID: 18350541
DOI: 10.1002/eji.200738067

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