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Macrophage polarization and bacterial infections

11 Feb 2011

Abstract excerpt

PURPOSE OF REVIEW: Macrophages are the first line of defense against pathogens, and the mode of their activation will determine the success or failure of the host response to pathogen aggression. Based on limited numbers of markers, activated macrophages can be classified as classically activated (M1) macrophages that support microbicidal activity or alternatively activated (M2) macrophages that are not competent...

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PMID: 21311324
DOI: 10.1097/qco.0b013e328344b73e

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