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Article

Phenotypic Diversity and Emerging New Tools to Study Macrophage Activation in Bacterial Infectious Diseases

10 Oct 2014

Abstract excerpt

Macrophage polarization is a concept that has been useful to describe the different features of macrophage activation related to specific functions. Macrophage polarization is responsible for a dichotomic approach (killing vs. repair) of the host response to bacteria; M1-type conditions are protective, whereas M2-type conditions are associated with bacterial persistence. The use of the polarization concept to...

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PMID: 25346736
DOI: 10.3389/fimmu.2014.00500

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