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Article

Assessing long-distance RNA sequence connectivity via RNA-templated DNA-DNA ligation.

eLife - 13 Apr 2015

Roy Christian K, Olson Sara, Graveley Brenton R, Zamore Phillip D, Moore Melissa J

Abstract excerpt

Many RNAs, including pre-mRNAs and long non-coding RNAs, can be thousands of nucleotides long and undergo complex post-transcriptional processing. Multiple sites of alternative splicing within a single gene exponentially increase the number of possible spliced isoforms, with most human genes currently estimated to express at least ten. To understand the mechanisms underlying these complex isoform expression...

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Identifiers

PMID: 25866926
DOI: 10.7554/eLife.03700
PMCID: PMC4442144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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