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Article

The structure-function role of C-terminus in human bitter taste receptor T2R4 signaling.

Biochimica et biophysica acta - 1 Jul 2015

Upadhyaya Jasbir, Singh Nisha, Bhullar Rajinder P, Chelikani Prashen

Abstract excerpt

Bitter taste, in humans, is sensed by 25 G protein-coupled receptors, referred to as bitter taste receptors (T2Rs). The diverse roles of T2Rs in various extraoral tissues have implicated them as a potential target for therapeutic intervention. Structure-function studies have provided insights into the role of transmembrane and loop regions in the activation mechanism of T2Rs. However, studies aimed at deciphering...

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Identifiers

PMID: 25858111
DOI: 10.1016/j.bbamem.2015.03.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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