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Article

Effects of MBL2 polymorphisms in patients with diisocyanate-induced occupational asthma.

Experimental & molecular medicine - 10 Apr 2015

Kim Seung-Hyun, Bae Su-Jin, Palikhe Sailesh, Ye Young-Min, Park Hae-Sim

Abstract excerpt

Diisocyanate (DI) is the most common cause of occupational asthma (OA) in Korea. Mannose-binding lectin (MBL) initiates the lectin complement activation pathway following oxidative stress and plays an important role in the regulation of inflammatory processes. To determine whether there is a genetic association between MBL2 polymorphisms and DI-OA, 99 patients with DI-OA, 99 asymptomatic exposed controls (AECs)...

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Source

Identifiers

PMID: 25857450
DOI: 10.1038/emm.2015.10

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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