Article
Genetic association study between mbl2 and asthma phenotypes in Chinese children.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Nov 2006
Leung Ting Fan, Tang Nelson L S, Sung Ying Man, Li Chung Yi, Ma Suk Ling, Lam Christopher W K, Wong Gary W K
Abstract excerpt
Mannose-binding lectin (MBL), a member of the innate immune system, initiates complement deposition on microbial surfaces. MBL deficiency is associated with severe respiratory infections. Polymorphisms in the MBL gene (mbl2) were associated with the susceptibility and severity of autoimmune diseases. This study investigated whether mbl2 polymorphisms at positions -550 and -221 and at codon-54 are associated with...
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