Article
Analysis of mannose-binding lectin 2 (MBL2) genotype and the serum protein levels in the Korean population.
Molecular immunology - 1 May 2005
Lee Seong-Gene, Yum Jung-Sun, Moon Hong Mo, Kim Hyun Jung, Yang Yun Joo, Kim Hie-Lim, Yoon Yongsook, Lee Sunyoung, Song Kyuyoung
Abstract excerpt
Mannose-binding lectin (MBL) is a C-type lectin produced by the liver and involved in the innate immune response. We have analyzed six SNPs of MBL2 gene--three at promoter (-550, -435, and -221), one at 5'-untranslational region (UTR) (+4), and two at coding (Gly54Asp and Leu126Leu) regions--in the Korean population (N=129), and have correlated genotypes with the serum concentration and functional...
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