Article
Genetic polymorphisms and expression of HLA-G and its receptors, KIR2DL4 and LILRB1, in non-small cell lung cancer.
Tissue antigens - 1 Jun 2015
Wiśniewski A, Kowal A, Wyrodek E, Nowak I, Majorczyk E, Wagner M, Pawlak-Adamska E, Jankowska R, Ślesak B, Frydecka I, Kuśnierczyk P
Abstract excerpt
Human leukocyte antigen-G (HLA-G) is a nonclassical HLA class I molecule absent from most normal tissues but detected in many malignant tumors. It is recognized by cells of the immune system using LILRB1, KIR2DL4 and LILRB2 receptors. We attempted to find out whether some polymorphisms of HLA-G, LILRB1 and KIR2DL4 genes are associated with susceptibility to nonsmall cell lung cancer (NSCLC). Four polymorphisms in...
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