Article
KIR2DL2/S2 and HLA-C C1C1 genotype is associated with better response to treatment and prolonged survival of patients with non-small cell lung cancer in a Polish Caucasian population.
Human immunology - 1 Sept 2012
Wiśniewski Andrzej, Jankowska Renata, Passowicz-Muszyńska Ewa, Wiśniewska Elżbieta, Majorczyk Edyta, Nowak Izabela, Frydecka Irena, Kuśnierczyk Piotr
Abstract excerpt
Non-small cell lung carcinoma (NSCLC) is a multifactorial disease influenced by both environmental and genetic factors. Here, we examined whether the repertoire of genes encoding killer immunoglobulin-like receptors (KIR) and genes for their ligands, C1/C2 and Bw4, may affect a susceptibility to NSCLC and response to treatment. We typed 269 NSCLC patients and 690 healthy control individuals for KIR genes and for...
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