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Natural killer cell killer immunoglobulin-like gene receptor polymorphisms in non-Hodgkin lymphoma: possible association with clinical course.

Leukemia & lymphoma - 1 Jan 2015

Pamuk Gulsum Emel, Tozkir Hilmi, Uyanik Mehmet Sevki, Gurkan Hakan, Duymaz Julide, Pamuk Omer Nuri

Abstract excerpt

Natural killer (NK) cell killer immunoglobulin-like receptors (KIRs) contribute to the pathogenesis of many diseases. We determined the association between polymorphisms of KIR and their ligands and susceptibility to non-Hodgkin lymphoma (NHL), clinical features and prognosis. We included 90 patients with NHL and 94 controls. In the NHL group, KIR2DS1, HLA-Bw4 (Thr80) and HLA-Bw4 (Thr80)+/Bw4 (Iso80)- ligands...

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Case-Control Studies
Genetic Association Studies
HLA Antigens
Ligands
Lymphoma, Non-Hodgkin

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PMID: 25699652
DOI: 10.3109/10428194.2015.1014361

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