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Genetic variants in the human leukocyte antigen region and survival of Chinese patients with non-small cell lung carcinoma.

Carcinogenesis - 24 Sept 2020

Cheng Lei, Liu Qi, Wang Mengyun, Gu Yanzi, Wang Jialei, Wei Qingyi, Zhang Ruoxin

Abstract excerpt

Human leukocyte antigen (HLA) is highly polymorphic, driving antigen presentation, complement cascade and leukocyte maturation against cancer cells. Therefore, we extracted genotyping data in the HLA region from an ongoing Chinese genome-wide association study of non-small cell lung cancer (NSCLC). Using deep sequencing data of 10 689 healthy Han Chinese, we imputed for untyped genetic variants in the HLA region,...

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Identifiers

PMID: 32614429
DOI: 10.1093/carcin/bgaa066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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