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Article

KIR-HLA gene diversities and susceptibility to lung cancer.

Scientific reports - 14 Oct 2022

Hematian Larki Marjan, Ashouri Elham, Barani Shaghik, Ghayumi Seiyed Mohammad Ali, Ghaderi Abbas, Rajalingam Raja

Abstract excerpt

Killer-cell immunoglobulin-like receptors (KIR) are essential for acquiring natural killer (NK) cell effector function, which is modulated by a balance between the net input of signals derived from inhibitory and activating receptors through engagement by human leukocyte antigen (HLA) class I ligands. KIR and HLA loci are polygenic and polymorphic and exhibit substantial variation between individuals and...

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Share to Gene Frequency
Share to Genotype
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA Antigens

Share to Immunoglobulins

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Share to Lung Neoplasms

Share to Receptors, KIR

Source

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Identifiers

PMID: 36241658
DOI: 10.1038/s41598-022-21062-1
PMCID: PMC9568660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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