Article

Natural killer cell educating KIR/HLA combinations impact survival in anti-PD-L1 treated cancer patients

2022-12-07

Abstract excerpt

Natural killer (NK) cells are educated through the binding of killer immunoglobulin like receptors (KIR) to human leukocyte antigen (HLA) proteins, but it is unknown whether the presence of these highly diverse KIR/HLA interactions influence responses to immunotherapy in solid tumors. We report herein two observations that shed light on NK cell function and abundance in anti-tumor immune responses. In patients wit...

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Literature Corpus work: d8100919-96d3-5201-810f-64d3e8632fd5
DOI: 10.1101/2022.12.06.22282592

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