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Article

Overexpression of CD97 confers an invasive phenotype in glioblastoma cells and is associated with decreased survival of glioblastoma patients.

PloS one - 1 Jan 2013

Safaee Michael, Clark Aaron J, Oh Michael C, Ivan Michael E, Bloch Orin, Kaur Gurvinder, Sun Matthew Z, Kim Joseph M, Oh Taemin, Berger Mitchel S, Parsa Andrew T

Abstract excerpt

Mechanisms of invasion in glioblastoma (GBM) relate to differential expression of proteins conferring increased motility and penetration of the extracellular matrix. CD97 is a member of the epidermal growth factor seven-span transmembrane family of adhesion G-protein coupled receptors. These proteins facilitate mobility of leukocytes into tissue. In this study we show that CD97 is expressed in glioma, has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23658650
DOI: 10.1371/journal.pone.0062765
PMCID: PMC3637305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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