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Integration of RNA-Seq and proteomics data identifies glioblastoma multiforme surfaceome signature

23 Jul 2021

Abstract excerpt

BACKGROUND: Glioblastoma multiforme (GBM) is a highly lethal, stage IV brain tumour with a prevalence of approximately 2 per 10,000 people globally. The cell surface proteins or surfaceome serve as information gateway in many oncogenic signalling pathways and are important in modulating cancer phenotypes. Dysregulation in surfaceome expression and activity have been shown to promote tumorigenesis. The expression...

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PMID: 34301218
DOI: 10.1186/s12885-021-08591-0

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