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Article

Interferon lambda 4 genotypes and resistance-associated variants in patients infected with hepatitis C virus genotypes 1 and 3.

Hepatology (Baltimore, Md.) - 1 Jan 2016

Peiffer Kai-Henrik, Sommer Lisa, Susser Simone, Vermehren Johannes, Herrmann Eva, Döring Matthias, Dietz Julia, Perner Dany, Berkowski Caterina, Zeuzem Stefan, Sarrazin Christoph

Abstract excerpt

UNLABELLED: Single-nucleotide polymorphisms (SNPs) in the interferon lambda 4 (IFNL4) gene are predictors for treatment success in patients with hepatitis C virus (HCV) infection. For direct-acting antiviral combinations only weak association with IFNL4 SNPs was observed. Little is known about potential selections of resistance-associated variants (RAVs) by the IFNL4 genotype. This study analyzed the prevalence...

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Identifiers

PMID: 26406534
DOI: 10.1002/hep.28255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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