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Article

Ethyl methanesulfonate induces mutations in Caenorhabditis elegans embryos at a high frequency.

Mutation research - 1 Jan 2000

Hartman Phil S, Barry James, Finstad Whitney, Khan Numan, Tanaka Masayuki, Yasuda Kayo, Ishii Naoaki

Abstract excerpt

Mutagenesis protocols typically call for exposure of late-stage larvae or adults to a mutagen with the intention of inducing mutations in a robust germ line. Instead, ca. 16,000 CB665 [unc-58(e665)] one- to four-cell embryos of the nematode Caenorhabditis elegans were hand selected and exposed to...

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Identifiers

PMID: 25847271
DOI: 10.1016/j.mrfmmm.2014.05.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25847271-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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