Article
Natural and unanticipated modifiers of RNAi activity in Caenorhabditis elegans.
PloS one - 1 Jan 2012
Asad Nadeem, Aw Wen Yih, Timmons Lisa
Abstract excerpt
Organisms used as model genomics systems are maintained as isogenic strains, yet evidence of sequence differences between independently maintained wild-type stocks has been substantiated by whole-genome resequencing data and strain-specific phenotypes. Sequence differences may arise from replication errors, transposon mobilization, meiotic gene conversion, or environmental or chemical assault on the genome. Low...
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