Article
Methods for creating mutations in C. elegans that extend lifespan.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Wang Dayong, Cao Min, Dinh Jessica, Dong Yuqing
Abstract excerpt
The principle of commonly used methods to create mutations in the nematode Caenorhabditis elegans (C. elegans) is straightforward. In general, worms are exposed to a dose of mutagen resulting in DNA damages and mutations. Screening the progeny of the mutagenized animals for a certain phenotype is...
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