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Article

Quantitative trait locus mapping of acute functional tolerance in the LXS recombinant inbred strains.

Alcoholism, clinical and experimental research - 1 Apr 2015

Bennett Beth, Larson Colin, Richmond Phillip A, Odell Aaron T, Saba Laura M, Tabakoff Boris, Dowell Robin, Radcliffe Richard A

Abstract excerpt

BACKGROUND: We previously reported that acute functional tolerance (AFT) to the hypnotic effects of alcohol was significantly correlated with drinking in the dark (DID) in the LXS recombinant inbred panel, but only in mice that had been pretreated with alcohol. Here, we have conducted quantitative trait locus (QTL) mapping for AFT. DNA sequencing of the progenitor ILS and ISS strains and microarray analyses were...

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Identifiers

PMID: 25833023
DOI: 10.1111/acer.12678
PMCID: PMC4384187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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