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Identification of ethanol analgesia quantitative trait loci and candidate genes in BXD recombinant inbred mouse lines.

Addiction biology - 1 Feb 2025

Rogers Walker D, Presley Alyssa, Damaj M Imad, Miles Michael F

Abstract excerpt

Alcohol consumption produces acute analgesic effects, and people experiencing pain conditions may drink alcohol to alleviate discomfort. However, tolerance to the analgesic properties of alcohol could prompt escalating consumption and dependence. Both nociception and alcohol-induced analgesia are under significant genetic control. Understanding the genetic architecture of these processes could inform better...

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PMID: 39996569
DOI: 10.1111/adb.70013
PMCID: PMC11851315

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