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Article

Quantitative trait locus mapping for acute functional tolerance to ethanol in the L x S recombinant inbred panel.

Alcoholism, clinical and experimental research - 1 Feb 2007

Bennett Beth, Downing Chris, Carosone-Link Phyllis, Ponicsan Heather, Ruf Cathy, Johnson Thomas E

Abstract excerpt

BACKGROUND: Acute functional tolerance (AFT) develops shortly after ethanol administration, and is determined as the change in brain or blood ethanol concentration (BEC) measured at 2 behavioral or physiological endpoints. Acute functional tolerance studies in some rodent strains support a long-held hypothesis that more sensitive strains develop more within-session tolerance. We used the new, 74-strain L x S...

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PMID: 17250610
DOI: 10.1111/j.1530-0277.2006.00296.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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