Article
SWI/SNF chromatin-remodeling complexes function in noncoding RNA-dependent assembly of nuclear bodies.
Proceedings of the National Academy of Sciences of the United States of America - 7 Apr 2015
Kawaguchi Tetsuya, Tanigawa Akie, Naganuma Takao, Ohkawa Yasuyuki, Souquere Sylvie, Pierron Gerard, Hirose Tetsuro
Abstract excerpt
Paraspeckles are subnuclear structures that form around nuclear paraspeckle assembly transcript 1 (NEAT1) long noncoding RNA (lncRNA). Recently, paraspeckles were shown to be functional nuclear bodies involved in stress responses and the development of specific organs. Paraspeckle formation is initiated by transcription of the NEAT1 chromosomal locus and proceeds in conjunction with NEAT1 lncRNA biogenesis and a...
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