Article
Genetic polymorphisms of NAMPT related with susceptibility to esophageal squamous cell carcinoma.
BMC gastroenterology - 21 Apr 2015
Zhang Chuanzhen, Yan Daojie, Wang Shanshan, Xu Changqing, Du Wenjun, Ning Tao, Liu Changhong, Zhang Meijuan, Hou Ruiping, Chen Ziping
Abstract excerpt
BACKGROUND: Nicotinamide phosphoribosyl transferase (Nampt) plays a crucial role in tumorigenesis. The present study examines whether genetic polymorphisms of NAMPT are related to the risk of developing esophageal squamous cell carcinoma (ESCC). METHODS: A total of 810 subjects were enrolled in this study, including 405 ESCC patients and 405 healthy controls. Using polymerase chain reaction-restriction fragment...
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