Article
Correlation between genetic variations and serum level of interleukin 28B with virus genotypes and disease progression in chronic hepatitis C virus infection.
Journal of immunology research - 1 Jan 2015
Al-Qahtani Ahmed, Al-Anazi Mashael, Abdo Ayman A, Sanai Faisal M, Al-Hamoudi Waleed, Alswat Khalid A, Al-Ashgar Hamad I, Khan Mohammed Q, Albenmousa Ali, Khalaf Nisreen, Viswan Nisha, Al-Ahdal Mohammed N
Abstract excerpt
Recent studies have demonstrated that polymorphisms near the interleukin-28B (IL-28B) gene could predict the response to Peg-IFN-a/RBV combination therapy in HCV-infected patients. The aim of the study was to correlate the serum level of IL28B in HCV-infected patients with virus genotype/subgenotype and disease progression. IL28B serum level was detected and variations at five single nucleotide polymorphisms...
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