Article
Effect of IL28B genotype on hepatitis B and C virus infection.
Current opinion in virology - 1 Oct 2015
Stättermayer Albert Friedrich, Ferenci Peter
Abstract excerpt
Genetic factors play a major role for treatment response and disease progression of chronic hepatitis B (HBV) and C virus (HCV) infection. In 2009 a genome-wide association study (GWAS) identified a single nucleotide polymorphism near the IL28B gene that was associated with treatment-induced viral clearance in chronic HCV infection treated with pegylated interferon-α (PEG-IFN) and ribavirin (RBV). Further,...
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