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Article

Role of serum level and genetic variation of IL-28B in interferon responsiveness and advanced liver disease in chronic hepatitis C patients.

Medical microbiology and immunology - 1 Apr 2017

Alborzi Abdolvahab, Hashempour Tayebeh, Moayedi Javad, Musavi Zahra, Pouladfar Gholamreza, Merat Shahin

Abstract excerpt

Interleukin-28B (IL-28B) is suspected to be associated with response to treatment and one of the basic immunological backgrounds in liver transplant candidate (LTC). We aimed to assess whether genotypes of IL-28B can play a role in therapeutic response or advanced stages of liver disease. A total of 364 subjects were genotyped for IL-28B rs12979860 and rs8099917 SNPs using PCR-RFLP assay. Moreover, IL-28 serum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28214926
DOI: 10.1007/s00430-017-0497-y

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