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Article

Mutations in TERT promoter and FGFR3 and telomere length in bladder cancer.

International journal of cancer - 1 Oct 2015

Hosen Ismail, Rachakonda P Sivaramakrishna, Heidenreich Barbara, de Verdier Petra J, Ryk Charlotta, Steineck Gunnar, Hemminki Kari, Kumar Rajiv

Abstract excerpt

Mutations in the promoter of the telomerase reverse transcriptase (TERT) and fibroblast growth factor receptor 3 (FGFR3) genes constitute the most recurrent somatic alterations in urothelial carcinoma of bladder. In this study, we screened DNA from 327 urothelial bladder carcinomas from well-documented patients, with different stages and grades and known TERT promoter mutational status, for FGFR3 alterations and...

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Share to FGFR3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Promoter Regions, Genetic

Share to Receptor, Fibroblast Growth Factor, Type 3

Share to Telomerase

Share to Telomere

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 25809917
DOI: 10.1002/ijc.29526

Genes

TERT
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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