Article
Biological significance of TERT promoter mutation in papillary urothelial neoplasm of low malignant potential.
Histopathology - 1 Apr 2018
Wang Chung-Chieh, Huang Chao-Yuan, Jhuang Yu-Lin, Chen Chih-Chi, Jeng Yung-Ming
Abstract excerpt
AIMS: Mutations in FGFR3 and the promoter region of the telomerase reverse transcriptase (TERT) gene have been found frequently in urothelial carcinoma of the urinary bladder. However, related data for papillary urothelial neoplasm of low malignant potential (PUNLMP) are limited. In this study, we investigated the mutation status of the TERT promoter, FGFR3 and HRAS in low-grade papillary urothelial neoplasms and...
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