Article
The genetic difference between Western and Chinese urothelial cell carcinomas: infrequent FGFR3 mutation in Han Chinese patients.
Oncotarget - 3 May 2016
Yuan Xiaotian, Liu Cheng, Wang Kun, Liu Li, Liu Tiantian, Ge Nan, Kong Feng, Yang Liu, Björkholm Magnus, Fan Yidong, Zhao Shengtian, Xu Dawei
Abstract excerpt
Urothelial cell carcinoma (UCC) includes urothelial bladder carcinoma (UBC), renal pelvic carcinoma (RPC) and ureter carcinoma (UC), and its incidence varies dependent on geographical areas and tumor locations, which indicates different oncogenic mechanisms and/or different genetic susceptibility/environment exposure. The activating mutations of the fibroblast growth factor receptor 3 (FGFR3) gene and telomerase...
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